July312014

breakingdownscience:

bbsrc:

Signal may send cancer’s cellular factories into overdrive

A network of signals active in almost all types of cancer sends the protein factories in our cells into overdrive, and may help fuel a tumour’s uncontrolled growth, new research suggests.

Scientists at The Institute of Cancer Research, one of the world’s most influential cancer research institutes, identified a molecular trigger responsible for ramping up activity of the endoplasmic reticulum (ER) – the cellular factory that makes the building blocks cancer cells need to keep growing.

The findings may help to explain how cancer cells maintain their high levels of metabolism – and could uncover future targets for cancer treatment

The top three images show human hepatocarcinoma cells with the endoplasmic reticulum (blue) and nucleus (red). Copyright: Dr Chris Bakal, The Institute of Cancer Research, London.

The bottom image shows human epithelial cells from breast tissue treated with Torin, an inhibitor of TOR kinase, where the endoplasmic reticulum is (green), nuclei (red) and F-actin (grey) Copyright: Dr Chris Bakal, The Institute of Cancer Research, London.

Read more: http://www.bbsrc.ac.uk/news/health/2014/140709-pr-signal-may-send-cancer-into-overdrive.aspx

A network of signals active in almost all types of cancer sends the protein factories in our cells into overdrive, and may help fuel a tumour’s uncontrolled growth, new research suggests.”
THIS IS NOT NEWS.  THE NEWS IS HOW THIS PROCESS IS CONTROLLED (VIA THE TOR KINASE PATHWAY)

(via nursingisinmyblood)

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tuileries:

A.F. Vandevorst installation for Arnhem Mode Biennale 2011

“A girl sleeping in a hospital bed in her A.F. Vandevorst dress. But here, the girl as well as the mattress and pillow are made out of candle wax. Once lit, what starts as a perfect image will slowly melt and perish during the biennale.”

(via cutieonthekawasaki)

3AM

(Source: afterdvrk, via cutieonthekawasaki)

12AM

I think I might be going mildly insane.

I’ve always felt like it really, I dance between being to optimistic and too pessimistic. I hop around motivation and a deep lackluster form of depression. Somedays I feel like quitting my job, school, everything and running off to live in a whole in the middle of the ocean. 

I dream of being productive and fitting into some mold where I can finally be happy, yet at the end of the day sometimes I think of killing myself.

Who knows where this world leads, if the aurora lights will ever shine on my pale skin, if I will ever climb up a mountain, fit in a size 4 dress, eat food with out thinking, dance in the middle of the rain with no cares, have children who I brush the hair of and see the world in their eyes. 

Best friends don’t exist in my world, everything is temporary, everyone leaves, everyone dies. I think of what it would be like to kill someone, bloody or not, just the image of their life leaving their eyes.

This isn’t normal and this isn’t good but I can’t change the way I exist. I want to sit in the dark, a hundred candles dripping wax while I sink face first into a pool of cold water, the rush of my skin  against ice, the feel of my face pressed to the bottom, my lungs hurting from the strain of no oxygen, heart beating fast as panic sets in. Then I’ll slowly emerge and I will feel the cold air dance across my goosebump ridden skin.

I think I just want to feel alive.

I think I miss drugs.

Or violence, I want to feel the rush of pain from being beat, the bloody taste in my mouth when my lips busted. Searing burn from a slap, anything I want to feel anything 

July302014
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